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抗原反應(yīng)的解釋
2020-01-06 20:26
所謂抗原的反應(yīng)原性是指能與由它刺激所產(chǎn)生的抗體或致敏淋巴細(xì)胞發(fā)生特異性反應(yīng)。具備免疫原性和反應(yīng)原性兩種能力的物質(zhì)稱為完全抗原，如病原體、異種動(dòng)物血清等。只具有反應(yīng)原性而沒有免
抗原的反應(yīng)
抗原的反應(yīng)疫原性的物質(zhì)，稱為半抗原，如青霉素、磺胺等。半抗原沒有免疫原性，不會(huì)引起免疫反應(yīng)。但在某些特殊情況下，如果半抗原和大分子蛋白質(zhì)結(jié)合以后，就獲得了免疫原性而變成完全抗原，也就可以刺激免疫系統(tǒng)產(chǎn)生抗體和效應(yīng)細(xì)胞。在青霉素進(jìn)入體內(nèi)后，如果其降解產(chǎn)物和組織蛋白結(jié)合，就獲得了免疫原性，并刺激免疫系統(tǒng)產(chǎn)生抗青霉素抗體。當(dāng)青霉素再次注射人體內(nèi)時(shí)，抗青霉素抗體立即與青霉素結(jié)合，產(chǎn)生病理性免疫反應(yīng)，出現(xiàn)皮疹或過敏性休克，甚至危及生命。
Antigenic reactivity is defined as the ability to react specifically to an antibody or lymphocyte produced by its stimulation. The immunogenicity and reactivity of two kinds of ability of the material known as complete antigen, such as pathogens, xenogeneic animal serum. A reactive immunogenic substance, called a Hapten, such as penicillin or sulfanilamide, that is reactive in nature but not immune to the antigen. Haptens have no immunogenicity and do not cause an immune response. However, in some special cases, if the hapten and the macromolecule protein after binding, they have acquired immunogenicity and become a complete antigen, which can stimulate the immune system to produce antibodies and effector cells. When penicillin enters the body, if its degradation products bind to tissue proteins, it acquires immunogenicity and stimulates the immune system to produce anti-penicillin antibodies. When Penicillin is re-injected into the body, anti-penicillin antibodies immediately bind to penicillin, producing a pathological immune response, a rash or Anaphylaxis, or even life-threatening
Antigenic reactivity is defined as the ability to react specifically to an antibody or lymphocyte produced by its stimulation. The immunogenicity and reactivity of two kinds of ability of the material known as complete antigen, such as pathogens, xenogeneic animal serum. A reactive immunogenic substance, called a Hapten, such as penicillin or sulfanilamide, that is reactive in nature but not immune to the antigen. Haptens have no immunogenicity and do not cause an immune response. However, in some special cases, if the hapten and the macromolecule protein after binding, they have acquired immunogenicity and become a complete antigen, which can stimulate the immune system to produce antibodies and effector cells. When penicillin enters the body, if its degradation products bind to tissue proteins, it acquires immunogenicity and stimulates the immune system to produce anti-penicillin antibodies. When Penicillin is re-injected into the body, anti-penicillin antibodies immediately bind to penicillin, producing a pathological immune response, a rash or Anaphylaxis, or even life-threatening
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