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梅毒TP檢測要多久
2019-05-06 11:37
梅毒的診斷應(yīng)十分認(rèn)真仔細(xì)、因?yàn)樗驮S多其它疾病的表現(xiàn)有相似之處，表現(xiàn)多樣，復(fù)雜且病程很長，有很長的時(shí)間處于潛伏狀態(tài)，診斷時(shí)必須結(jié)合病史，體格檢查及化驗(yàn)結(jié)果，進(jìn)行綜合分析判斷，必要時(shí)還需進(jìn)行追蹤隨訪，家庭調(diào)查和試驗(yàn)治療等輔助方法。 一、病史： ?。ㄒ唬?不潔性交史：應(yīng)盡量詢問患者的嫖娼史或其他不潔性交史以確定傳染源。如肛門有硬下疳，應(yīng)詢問是否有肛交史。問清楚不潔性交的時(shí)間，對(duì)于確定梅毒的潛伏期是十分必要的。 ?。ǘ?現(xiàn)病史：有無陰部潰爛、皮膚紅斑、丘疹、濕疣史，有否發(fā)生過硬下疳、二、三期梅毒史。梅毒血清學(xué)試驗(yàn)檢測情況。 ?。ㄈ?婚姻史：有無涉外婚姻，結(jié)婚次數(shù)，配偶有無性病或可疑性病的臨床表現(xiàn)等。 ?。ㄋ模?分娩史：有無先兆流產(chǎn)、早產(chǎn)、流產(chǎn)和死產(chǎn)的病史，過去有無分娩胎傳梅毒兒史。 ?。ㄎ澹?如有可疑先天性梅毒，應(yīng)詢問父母是否患過梅毒，及兄弟姐妹受染情況及本人有無早期和晚期梅毒的癥狀和體征。 ?。?如懷疑潛伏梅毒，詢問傳染史以及有無存在致使血清試驗(yàn)生物學(xué)假陽性的疾病。 ?。ㄆ撸?治療史：是否做過驅(qū)梅治療，用藥劑量及療程，是否正規(guī)，有無藥物過敏史等。 二、體格檢查 （一） 一般檢查：生長發(fā)育狀況是否良好，精神狀態(tài)情況； （二） 皮膚粘膜：根據(jù)早期和晚期梅毒的皮膚損害特點(diǎn)仔細(xì)檢查全身皮膚、粘膜、淋巴結(jié)、毛發(fā)、生殖器官、肛門、口腔等。 （三） 特殊檢查：眼、骨骼系統(tǒng)、心臟及神經(jīng)系統(tǒng)的深入檢查或進(jìn)行專科檢查。 三、實(shí)驗(yàn)室檢查： （一） 早期梅毒應(yīng)做梅毒螺旋體暗視野顯微鏡檢查。 ?。ǘ?梅毒血清反應(yīng)素試驗(yàn)（如VDRL、USR或RPR試驗(yàn)），有必要時(shí)再做螺旋體 抗原試驗(yàn)（如FTA-ABS或TPHA試驗(yàn)）。 （三） 腦脊液檢查，以除外神經(jīng)梅毒，尤其無癥狀神經(jīng)梅毒，早期梅毒即可有神經(jīng)損害，二期梅毒有35%的病人腦脊液異常，因此要檢查腦脊液。 ?。ㄋ模┗蛟\斷檢測。
The diagnosis of syphilis should be very careful, because it has similarities with many other diseases. It is diverse, complex, and has a long course of disease. It has a long period of latent state. The diagnosis must be combined with medical history, physical examination and test results. Comprehensive analysis and judgment, if necessary, also need to carry out follow-up follow-up, household surveys and experimental treatment and other auxiliary methods. History:(1) History of impure intercourse: The patient's history of whoring or other impure intercourse should be asked as much as possible to determine the source of infection. If the anus has a hard chancre, you should ask if there is a history of anal sex. Asking the time of unclean sexual intercourse is very necessary to determine the incubation period of syphilis. (2) Current history: whether there is any history of genital ulceration, skin erythema, papules, and wet warts, and whether there is any history of severe diarrhea, second and third stage syphilis. Serology test of syphilis. (3) Marriage history: whether there is a foreign-related marriage, the number of marriages, whether the spouse has sexually transmitted diseases or suspicious sexually transmitted diseases, etc.. (4) History of childbirth: whether there is a history of threatened abortion, premature birth, abortion and stillbirth, and whether there has been a history of the transmission of plums in childbirth and childbirth in the past. (5) If there is suspicion of congenital syphilis, ask the parents whether they have suffered from syphilis, whether their brothers and sisters have been infected, and whether they have symptoms and signs of early and late syphilis. (6) if syphilis is suspected to be latent, to inquire about the history of infection and whether there are any diseases that cause false positives in serum test biology. (7) Treatment history: whether or not it has been treated with plum, dose and course of treatment, whether it is regular, and whether it has a history of drug allergies. Medical examination(1) General examination: whether the growth and development status is good, mental state; (2) Skin mucous membranes: the body's skin, mucous membranes, lymph nodes, hair, reproductive organs, anus, oral cavity, etc. are carefully examined according to the characteristics of skin damage caused by early and late syphilis. (III) Special examinations: in-depth examination or specialist examination of the eye, skeletal system, heart and nervous system. Laboratory examination:(1) Early syphilis should be examined with a spiral dark field microscope. (II) Syphilitic serum reactin tests(such as VDRL, USR or RPR tests), and when necessary, spiral antigen tests(such as FTA-ABS or TPHA tests). (3) Cerebrospinal fluid examination, with the exception of neurosyphilis, especially asymptomatic neurosyphilis, can cause nerve damage in early syphilis, and 35 % of patients with secondary syphilis have abnormal cerebrospinal fluid, so cerebrospinal fluid should be checked. (4) genetic diagnosis and detection.
The diagnosis of syphilis should be very careful, because it has similarities with many other diseases. It is diverse, complex, and has a long course of disease. It has a long period of latent state. The diagnosis must be combined with medical history, physical examination and test results. Comprehensive analysis and judgment, if necessary, also need to carry out follow-up follow-up, household surveys and experimental treatment and other auxiliary methods. History:(1) History of impure intercourse: The patient's history of whoring or other impure intercourse should be asked as much as possible to determine the source of infection. If the anus has a hard chancre, you should ask if there is a history of anal sex. Asking the time of unclean sexual intercourse is very necessary to determine the incubation period of syphilis. (2) Current history: whether there is any history of genital ulceration, skin erythema, papules, and wet warts, and whether there is any history of severe diarrhea, second and third stage syphilis. Serology test of syphilis. (3) Marriage history: whether there is a foreign-related marriage, the number of marriages, whether the spouse has sexually transmitted diseases or suspicious sexually transmitted diseases, etc.. (4) History of childbirth: whether there is a history of threatened abortion, premature birth, abortion and stillbirth, and whether there has been a history of the transmission of plums in childbirth and childbirth in the past. (5) If there is suspicion of congenital syphilis, ask the parents whether they have suffered from syphilis, whether their brothers and sisters have been infected, and whether they have symptoms and signs of early and late syphilis. (6) if syphilis is suspected to be latent, to inquire about the history of infection and whether there are any diseases that cause false positives in serum test biology. (7) Treatment history: whether or not it has been treated with plum, dose and course of treatment, whether it is regular, and whether it has a history of drug allergies. Medical examination(1) General examination: whether the growth and development status is good, mental state; (2) Skin mucous membranes: the body's skin, mucous membranes, lymph nodes, hair, reproductive organs, anus, oral cavity, etc. are carefully examined according to the characteristics of skin damage caused by early and late syphilis. (III) Special examinations: in-depth examination or specialist examination of the eye, skeletal system, heart and nervous system. Laboratory examination:(1) Early syphilis should be examined with a spiral dark field microscope. (II) Syphilitic serum reactin tests(such as VDRL, USR or RPR tests), and when necessary, spiral antigen tests(such as FTA-ABS or TPHA tests). (3) Cerebrospinal fluid examination, with the exception of neurosyphilis, especially asymptomatic neurosyphilis, can cause nerve damage in early syphilis, and 35 % of patients with secondary syphilis have abnormal cerebrospinal fluid, so cerebrospinal fluid should be checked. (4) genetic diagnosis and detection.