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實(shí)驗(yàn)室檢查 Laboratory examination
2017-01-16 10:50
實(shí)驗(yàn)室檢查L(zhǎng)aboratory examination
（1）暗視野顯微鏡檢查 取患者的可疑皮損（如硬下疳、扁平濕疣、濕丘疹等），在暗視野顯微鏡下檢查，見(jiàn)到可運(yùn)動(dòng)的梅毒螺旋體，可作為梅毒的確診依據(jù)。
(1) Treponema movement of the body, can be used as the basis of diagnosis of syphilis. Suspicious lesions of dark field microscope with (such as hard chancre, flat condyloma, wet papules etc.), check in the dark field microscope.
（2）梅毒血清學(xué)試驗(yàn) 梅毒血清學(xué)試驗(yàn)方法很多，所用抗原有非螺旋體抗原（心磷脂抗原）和梅毒螺旋體特異性抗原兩類(lèi)。前者有快速血漿反應(yīng)素環(huán)狀卡片試驗(yàn)（RPR）、甲苯胺紅不加熱血清學(xué)試驗(yàn)（TRUST）等，可做定量試驗(yàn)，用于判斷療效、判斷病情活動(dòng)程度。后者有梅毒螺旋體顆粒凝集試驗(yàn)（TPPA）、梅毒螺旋體酶聯(lián)免疫吸附試驗(yàn)（TP-ELISA）等，特異性強(qiáng)，用于TP感染的確證。
(2) There are many methods of Syphilis Serological Test for Syphilis Serological Test, and the antigen used in the test is non spiral antigen (cardiolipin antigen) and Treponema pallidum specific antigen (two). The former has a rapid plasma reactive element loop card test (RPR), toluidine red unheated serum test (TRUST), etc., can be used to determine the efficacy of quantitative tests to determine the extent of disease activity. The latter has Treponema pallidum particle agglutination test (TPPA), Treponema pallidum enzyme linked immunosorbent assay (TP-ELISA) and so on, which is highly specific for the confirmation of TP infection.
梅毒螺旋體IgM抗體檢測(cè)：感染梅毒后，首先出現(xiàn)IgM抗體，隨著疾病發(fā)展，IgG抗體隨后才出現(xiàn)并慢慢上升。經(jīng)有效治療后IgM抗
體消失，IgG抗體則持續(xù)存在。TP-IgM抗體不能通過(guò)胎盤(pán)，如果嬰兒TP-IgM陽(yáng)性則表示嬰兒已被感染，因此，TP-IgM抗體檢測(cè)對(duì)診斷嬰兒的胎傳梅毒意義很大。 Treponema pallidum IgM antibody detection: after the infection of syphilis, the first appearance of IgM antibodies, with the development of the disease, IgG antibody then appeared and slowly rising. After effective treatment, the IgM antibody disappeared and the IgG antibody persisted. TP-IgM antibody can not pass through the placenta, if the baby TP-IgM positive that the baby has been infected, therefore, TP-IgM antibody detection for the diagnosis of fetal transmission of syphilis is of great significance.
（1）暗視野顯微鏡檢查 取患者的可疑皮損（如硬下疳、扁平濕疣、濕丘疹等），在暗視野顯微鏡下檢查，見(jiàn)到可運(yùn)動(dòng)的梅毒螺旋體，可作為梅毒的確診依據(jù)。
(1) Treponema movement of the body, can be used as the basis of diagnosis of syphilis. Suspicious lesions of dark field microscope with (such as hard chancre, flat condyloma, wet papules etc.), check in the dark field microscope.
（2）梅毒血清學(xué)試驗(yàn) 梅毒血清學(xué)試驗(yàn)方法很多，所用抗原有非螺旋體抗原（心磷脂抗原）和梅毒螺旋體特異性抗原兩類(lèi)。前者有快速血漿反應(yīng)素環(huán)狀卡片試驗(yàn)（RPR）、甲苯胺紅不加熱血清學(xué)試驗(yàn)（TRUST）等，可做定量試驗(yàn)，用于判斷療效、判斷病情活動(dòng)程度。后者有梅毒螺旋體顆粒凝集試驗(yàn)（TPPA）、梅毒螺旋體酶聯(lián)免疫吸附試驗(yàn)（TP-ELISA）等，特異性強(qiáng)，用于TP感染的確證。
(2) There are many methods of Syphilis Serological Test for Syphilis Serological Test, and the antigen used in the test is non spiral antigen (cardiolipin antigen) and Treponema pallidum specific antigen (two). The former has a rapid plasma reactive element loop card test (RPR), toluidine red unheated serum test (TRUST), etc., can be used to determine the efficacy of quantitative tests to determine the extent of disease activity. The latter has Treponema pallidum particle agglutination test (TPPA), Treponema pallidum enzyme linked immunosorbent assay (TP-ELISA) and so on, which is highly specific for the confirmation of TP infection.
梅毒螺旋體IgM抗體檢測(cè)：感染梅毒后，首先出現(xiàn)IgM抗體，隨著疾病發(fā)展，IgG抗體隨后才出現(xiàn)并慢慢上升。經(jīng)有效治療后IgM抗
體消失，IgG抗體則持續(xù)存在。TP-IgM抗體不能通過(guò)胎盤(pán)，如果嬰兒TP-IgM陽(yáng)性則表示嬰兒已被感染，因此，TP-IgM抗體檢測(cè)對(duì)診斷嬰兒的胎傳梅毒意義很大。 Treponema pallidum IgM antibody detection: after the infection of syphilis, the first appearance of IgM antibodies, with the development of the disease, IgG antibody then appeared and slowly rising. After effective treatment, the IgM antibody disappeared and the IgG antibody persisted. TP-IgM antibody can not pass through the placenta, if the baby TP-IgM positive that the baby has been infected, therefore, TP-IgM antibody detection for the diagnosis of fetal transmission of syphilis is of great significance.